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haslamr

Richard Haslam

Role(s):
Senior Research Scientist
Biological Chemistry & Crop Protection
Harpenden
Summary:

Dr Richard Haslam is a Senior Research Scientist at Rothamsted Research. His main interest is in plant metabolism specifically the modification of seed oils. Working in the emerging field of Lipidomics; that studies the pathways and networks of cellular lipids in biological systems on a large scale; he investigates the dynamics of cellular lipids and the changes that occur in plants during development or perturbation. With the evolution of sophisticated mass spectrometers linked to highly efficient liquid chromatography systems, individual molecular species of lipids can now be isolated and identified, providing a new window onto this most diverse family of chemicals.  Knowledge of how plants control lipid metabolism provides an opportunity to enhance human nutrition, as well as production of lubricants, detergents and chemical feedstock's in seeds.

Phone:
+44 (0) 1582 763 133 ext: +44 1582 938200
Location:
Rothamsted Research, West Common, Harpenden, Hertfordshire, AL5 2JQ
Past Projects
Project Leader
  • IDG/Oil Production in the extreme
Member
  • Industrial crops producing added value oils for novel chemicals: ICON
  • Establishing a transatlantic platform for plant lipidomics
  • The role of lipids in determining gas bubble retention and stability in wheat dough
  • Understanding the role of lipases in controlling seed storage oil composition

2017

Mei C, Cussac M, Haslam RP, Beaudoin F, Wong Y-S, Marechal E, Rebeille F. (2017) metabolism inhibition and nirtogen inhibition deprivation trigger triacylglycerol accumulation in Arabidopsis thaliana cell cultures and highlights a role of NPC in phosphatidylcholine-to-triacylglycerol pathway. Frontiers in Plant Science. 4th Jan doi.org/10.3389/fpls.2016.02014.

2016

Haslam RP, Sayanova O, Jin Kim H, Cahoon EB, Napier JA. (2016) Synthetic redesign of plant lipid metabolism. Plant Journal doi: 10.1111/tpj.13172.

Ruiz Lopez N, Broughton R, Usher S, Salas J, Haslam RP, Napier JA, Beaudoin F. (2016) Tailoring the composition of novel wax esters in the seeds of transgenic Camelina sativa through systematic metabolic engineering. Plant Biotechnology Journal. doi: 10.1111/pbi.1267

Morineau C, Gissot L, Bellec Y, Hematy K, Tellier F, Renne C, Haslam RP, Beaudoin F, Napier JA, Faure J-D. (2016) Dual fatty acid elongase complex interactions in Arabidopsis. PLoS ONE 11(9): e016031. Doi:10.1371/journal.pone.0160631

Paya-Milans, M, Aznar-Moreno J,Balbuena TS, Haslam RP, Gidda SK, Perez-Hormaeche J, Mullen RT, Thelen JJ, Napier JA, Salas JJ, Garces R, Martinez-Force E, Venegas-Caleron M. (2016) Sunflower HaGPAT0-1 is the predominant GPAT during seed development. Plant Science 252:42-52 doi 10.1016/j.plantsci.20156.07.002

Popko J, Herrfurth C, Feussner K, Ischebeck T, Iven T, Haslam RP, Hamilton M, Sayanova O, Napier JA, Khozin-Goldberg I, Feussner I (2016) Metabolome analysis revelas betaine lipids as a major source for triglyceride formation and the accumulatin of sedoheptulose during nitrogen starvation of Phaeodactylum tricornutum. PLoS One 11(10): e0164673.

Hematy K, Bellec Y, Podeicheti R, Bouteiller N, Anne P, Morineau C, Haslam RP, Beaudoin F, Hapier JA, Mockaitis K, Gagliardi D, Vauchert H, Lange H, Faure J-D. (2016) the zinc-finger protein SOP1 is required for a subset of the nucler exosome functions in Arabidopsis. PLoS Genetics 12(2): e1005817 doi: 10.1371/jornal.pgen.1005817.

 

2015

Haslam RP, Usher S, Sayanova O, Napier JA, Betancor MB, Tocher D. (2015) The supply of fish oil to aquaculture: a role for transgenic oilseed crops? World Agriculture. Vol.5(2): 15-23.

Gonzalez-Thuillier I, Salt L, Chope G, Penson S, Skeggs P, Tosi P, Powers SJ, Ward JL, Wilde P, Shewry PR, Haslam RP (2015) Distribution of lipids in the grain of wheat (cv Hereward) determined by lipidomic analysis of milling and pearling fractions. Journal of Agriculture and Food Chemistry doi: 10.1021/acs.jafc.5b05229.

Napier JA, Usher S, Haslam RP, Ruiz-Lopez N, Sayanova O. (2015) Heterologous synthesis of omega-3 long chain polyunsaturated fatty acids in transgenic plants. European Journal of Lipid Science and Technology doi: 10.1002/ejlt.201400452.

Ruiz-Lopez N, Haslam R P, Usher S, Napier J A, Sayanova O. (2015) An alternative pathway for the effective production of the omega-3 long-chain polyunsaturates ETA and EPA in oilseeds. Plant Biotechnology Journal. Published Jan 30. doi: 10.1111/pbi.12328.

Haslam T, Haslam R P, Thoraval D, Pascal S, Delude C, Domergue F, Mañas Fernández A, Beaudoin F, Napier JA, Kunst L, Joubès J. (2015) CER2-LIKE Proteins have Unique Biochemical and Physiological Functions in Very-Long-Chain Fatty Acid Elongation. Plant Physiology. Published Jan 16. doi: pp.114.253195

Ruiz-Lopez N, Usher S, Sayanova O, Napier J A, Haslam R P. (2015) Modifying the lipid content and composition of plant seeds: engineering the production of LC-PUFA. Applied Microbiology and Biotechnology 99: 143-154.

2014

Hsiao, A-S, Haslam R P, Michaelson L V, Lao P, Chen Q-F, Sooriyaarachchi S, Mowbray S L, Napier J A, Tanner J A, Chye M-L. (2014) Arabidopsis cytosolic acyl-CoA-binding proteins ACBP4, ACBP5, and ACBP5 have overlapping but distinct roles in seed development. Bioscience Reports 34(6):art:e00165.doi:10.1042/BSR20140139.

Beaudoin F, Sayanova O, Haslam RP, Bancroft I, Napier JA. (2014) Oleaginous crops as integrated production platforms for food, feed, fuel and renewable industrial feedstock - Manipulation of plant lipid composition via metabolic engineering and new opportunities from association genetics for crop improvement and valorisation of co-products. OCL 21(6) D606 doi: http://dx.doi.org/10.1051/ocl/2014042

Dunne A, Maple-Grødem J, Gargano D, Haslam R P, Napier J A, Chua N-H, Russell R, Geir Møller S (2014) Modifying fatty acid profiles through a new cytokin-based plastid transformation system. Plant Journal 80(6):1131-1138.

Hsiao A S, Haslam R P, Michaelson L V, Liao P, Napier J A, Chye M L. (2014) Gene expression in plant lipid metabolism in Arabidopsis seedlings. PLoS One. 29:9(9):e107372.

Napier J A, Haslam R P, Beaudoin F, Cahoon E B. (2014) Understanding and manipulating plant lipid metabolism: metabolic engineering leads the way. Current Opinion in Plant Biology 19:68-75.

Azevedo R A, Lea P J, Leather S R, McNicol J W, Haslam R P, Valkonen J P T. (2014) The centenary of Annals of Applied Biology in 2014. Annals of Applied Biology 164: 1-7.

Ruiz-Lopez N, Haslam R P, Napier J A, Sayanova O. (2014) Successful high level accumulation of fish oil omega-3 long chain polyunsaturated fatty acids in a transgenic oilseed crop. Plant Journal 77: 198-208.

2013

Hamilton M L, Haslam R P, Napier J A, Sayanova O. (2013) Metabolic engineering of Phaeodactylum tricornutum for enhanced accumulation of omega-3 long chain polyunsaturated fatty acids. Metabolic Engineering 22(100): 3-9.

Haslam R P & Michaelson LV. (2013) Oil production in the Extreme. Annals of Applied Biology 163(2): 170-173.

Ruiz-Lopez N, Haslam R P, Usher S L, Sayanova O, Napier J A. (2013) Reconstitution of EPA and DHA biosynthesis in Arabidopsis: Iterative metabolic engineering for the synthesis of n-3 LC-PUFAs in transgenic plants. Metabolic Engineering 17: 30-41.

Pascal S, Bernard A, Sorel M, Pervent M, Vile D, Haslam R P, Napier J A, Domergue F, Lessire R, Joubes J. (2013) The Arabidopsis cer26 mutant, like the cer2 mutant, is specifically affected in the very-long-chain-fatty acid elongation process. Plant Journal 73(5): 733-746.

Haslam R P, Ruiz-Lopez N, Eastmond P, Moloney M, Sayanova O, Napier J A. (2013) The modification of plant oil composition by metabolic engineering - better nutrition by design. Plant Biotechnology Journal 11(2): 157-168.

Smith MA, Dauk M, Ramadan H, Yang H, Seamons L E, Haslam R P, Beaudoin F, Ramirez-Erosa I, Forseille L. (2013) Involvement of Arabidopsis ADS2 (At2g31360) in the biosynthesis of the very long chain monounsaturated fatty acid components of membrane lipids. Plant Physiology 161: 81-96

2012

Bernard A, Domergue F, Pascal S, Jetter R, Renne C, Faure J-D, Haslam R P, Napier J A, Lessire R, Joubes J. (2012) Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis CER1 and CER3 are core components of a VLC-alkane synthesis complex. Plant Cell 24: 3106-3118.

Andre C, Haslam R P, Shanklin J. (2012) Feedback regulation of plastidic acetyl-CoA carboxylase by 18:1-acyl carrier protein in Brassica napus. PNAS 109(25): 10107-10112. 

Ruiz-Lopez N, Haslam R P, Venegas-Caleron M, Li T, Bauer J, Napier J A, Sayanova O. (2012) Enhancing the accumulation of omega-3 long chain polyunsaturated fatty acids in transgenic Arabidopsis thaliana via iterative metabolic engineering and genetic crossing. Transgenic Research 21(6):1233-1243.

Ruiz-Lopez N, Sayanova O, Napier J A, Haslam R P. (2012) Metabolic engineering of the omega-3 long chain polyunsaturated fatty acid biosynthetic pathway into transgenic plants. Journal of Experimental Botany 63:2397-2410. 

2011

Fait A, Nunes Nesi A, Angelovici R, Lehmann M, Pham P A, Song L, Haslam R P, Napier J A, Galili G, Fernie A R. (2011) Targeted enhancement of glutamate to γ-aminobutyrate conversion in Arabidopsis seeds affects C-N balance and storage reserves in a development-dependent manner. Plant Physiology 157: 1026-1042.

Sayanova O, Ruiz-Lopez N, Haslam R P, Napier J A. (2011) The role of acyl-carrier specificity in the heterologous expression of the LC-PUFA biosynthetic pathway in transgenic plants. Plant Biotechnology Journal 10: 195-600.

Bourdenx B, BernardA, DomergueF, Pascal S, LégerA, RobyD, MarjorieP, Denis V, Haslam R P, Napier J A, Lessire R, Joubès J. (2011) Over expression of Arabidopsis CER1 promotes wax VLC-alkane biosynthesis and influences plant response to biotic and abiotic stresses in Arabidopsis. Plant Physiology 156: 29-45.

Sayanova O, Haslam R P, Venegas-Caleron M, Ruiz-Lopez N, Worhty C, Rooks P, Allen M, Napier J A. (2011) Identification and characterisation of genes encoding the omega-3 polyunsaturated biosynthetic pathway from the coccolithophore Emiliania huxleyi.  Phytochemistry 72 (7): 594-600.

Tavares S, GrotkjærT, Obsen T, Haslam R P, NapierJ A, GunnarssonN. (2011) Metabolic engineering of Saccharomyces cerevisiae for production of eicosapentaenoic acid using a novel Δ5-desaturase from Paramecium tetraurelia. Applied and Environmental Microbiology 77: 1854-1861.

Zadravec D, TvrdikP, Guillou H, HaslamR P, KobayashiT, Napier J A, CapecchiM R, Jacobsson A. (2011) ELOVL2 controls the level of w-6 28:5 and 30:5 very long-chain polyunsaturated fatty acids in testis, which are a prerequisite for male fertility and sperm maturation in mice. Journal of Lipid Research 52: 245 - 255.

2010

Napier J A & Haslam R P. (2010) As simple as ACB: new insights into the role of acyl-CoA binding proteins in Arabidopsis. New Phytologist 186(4): 781 - 783.

Roudier F, Gissot L, Beaudoin F, Haslam R P, Michaelson L V, Marion J, Molino D, Lima A, Bach L, Morin H, Tellier F, Palauqui J-C, Bellec Y, Miquel M, DaCosta M, Vignard J, Rochat C, Markham J E, Moreau P, Napier J A, Faure J-D. (2010) Very long chain fatty acids are involved in auxin transport and development patterning in Arabidopsis. Plant Cell 22: 364 - 375.

2009

Ruiz-Lopez N, Haslam R P, Venegas-Caleron M, Larson T R, Zank T, Graham I A, Napier J A, Sayanova O. (2009) The synthesis and accumulation of stearodonic acid in transgenic plants: a novel source of "heart healthy" omega-3 fatty acids. Plant Biotechnology Journal 7: 706 - 716.

Beaudoin F, Wu X, Li F, Haslam R P, Markham J E, Zheng H, Napier J A, Kunst L. (2009) Functional Characterization of the Arabidopsis thaliana -Ketoacyl-CoA Reductase Candidates of the Fatty Acid Elongase. Plant Physiology 150: 1174 - 1191.

Reina-Pinto J, Voisin D, Kurdyukov S, Faustich A, Haslam R P, Michaelson L V, Efremova N, Franke B, Schreiber L, Napier J A, Yephremov A. (2009) Missexpression of FATTY ACID ELONGATION (FAE1) in the Arabidopsis epidermis induces cell death and suggests a critical role for the phospholipase A2 in this process. Plant Cell 21: 1252 - 1272.

Michaelson L V, Zuner S, Markham J E, HaslamR P, Desikan R, MugfordS, Albrecht S, Warnecke D, Sperling P, Heinz E, Napier J A. (2009) Functional characterisation of a higher plant sphingolipid D4-desaturase: defining the role of sphingosine and sphingosine-1-phosphate in Arabidopsis thaliana. Plant Physiology 149: 487 - 498.

2008

Linka N, Theodoulou FL, Haslam R P, Napier J A, Neuhaus E, Weber A P M. (2008) Peroxisomal ATP import is essential for seedling development in Arabidopsis thaliana. Plant Cell 20: 3241 - 3257. Faculty1000 Recomended.

Bach L, Michaelson L V, Haslam R P, Bellec Y, Gissot L, Marion J, Da Costa M, Boutin J-P, Miquel M, Tellier F, Domergue F, Markham J E, Beaudoin F, Napier J A, Faure J-D. (2008). The very-long-chain hydroxy fatty acyl-CoA dehydratase PASTICCINO2 is essential and limiting for plant development. PNAS 105 (38): 14727 -14731.

2007

Sayanova O, Haslam R P, Venegas-Caleron M, Napier J A. (2007) Cloning and characterization of unusual fatty acid desaturases from Anemone leveillei: identification of an acyl-CoA C20 D5-desaturase responsible for the synthesis of sciadonic acid. Plant Physiology 144: 455 - 567.

2006

Sayanova O, Haslam R P, Guschina I, Lloyd D, Christie W W, Harwood J L, Napier J A. (2006) A bi-functional D12, D15 desaturase from Acanthamoeba castellanii directs the synthesis of highly unusual n-1 series fatty acids. Journal Biological Chemistry 281: 36533 - 36541.

Sayanova O, Haslam R P, Venegas-Caleron M, Napier J A. (2006) Isolation of front-end desaturases with distinct n-6 or n-3 substrate preferences from Primula species. Planta 224(6): 1269 - 1277.

Sayanova O, Haslam R P, Qi B , Lazarus C, Napier J A. (2006) Identification of an alternative pathway C20 D 8-desaturase from a non-photosynthetic organism, Acanthamoeba castellanii: identification of an atypical front-end desaturase. FEBS Letters 580:1946 - 1952.

Napier J A, Haslam R P, Venegas-Caleron M, Michaelson L V, Beaudoin F, Sayanova O. (2006) Progress towards the production of very long chain polyunsaturated fatty acid in transgenic plants: plant metabolic engineering comes of age. Physiologia Plantarum 126: 398 - 406.

2005

Haslam R P, Keys A J, Andralojc J, Madjwick P, Andersson I, Grimsrud A, Eilertsen H C, Parry M A J. (2005) Specificity of Diatom Rubisco Pages 157 - 164. K. Omasa, I. Nouchi, L. J. De Kok (Eds). Plant responses to air pollution and global change. Springer-Verlag Tokyo.

Coleman J O D, Haslam R P, Downie A L (2005) Transcriptomics and proteomics: tools for optimising phytoremediation activities. Zeitschrift fur Naturforschung C: Biosciences 60c: 544 -548.

Galmes J, Flexas, J, Keys A J, Cifre J, Mitchell R A C, Madgwick P J, Haslam R P, Medrano H, Parry M A J. (2005) Rubisco specificity factor tends to be larger in plant species from drier habitats and with persistent leaves. Plant Cell and Environment 28 : 571 - 580.

2004

Downie A L, Miyazaki S, Bohnert H J, John P, Coleman J O D, Parry M A J, Haslam R P. (2004) Expression profiling of the response of Arabidopsis thaliana to methanol stimulation. Phytochemistry 65 : 2305 - 2316 .

2003

Haslam R P, Downie A L, Raveton M, Gallardo K, Job D, Pallett K, John P, Parry M A J, Coleman J O D. (2003). The assessment of enriched apoplast extracts using proteomic approaches . Annals of Applied Biology 143 : 81 - 91.

Haslam R P, Borland A M, Maxwell K, Griffiths H. (2003) Physiological responses of the CAM epiphyte Tillandsia usneoides L . (Bromeliaceae) to variations in light and water supply . Journal of Plant Physiology 160 : 627 - 634.

2002

Haslam R P, Rust S, Cole D, Pallett K, Coleman J O D. (2002) Cloning and characterisation of S-formylglutathione hydrolase from Arabidopsis thaliana. Plant Physiology and Biochemistry 40 (4) : 281 - 288.

Haslam R P, Borland A M, Griffiths H. (2002). Short-term plasticity of CAM expression in the epiphytic bromeliad Tillandsia usneoides. Functional Plant Biology 29 (6) : 749 - 756.

Griffiths H, Helliker B, Roberts A, Haslam R P, Girnus J, Robe W, Borland A, Maxwell K. (2002) Regulation of Rubisco activity in CAM plants: better late than never. Functional Plant Biology 29 (6) : 689 - 696.

Dodd A N, Borland A M, Haslam R P, Griffiths H, Maxwell K. (2002) Crassulacean Acid Metabolism: plastic fantastic. Journal of Experimental Botany 53 (369): 569 - 580.

2001

Haslam R P, Raveton M, Cole D, Pallett K, Coleman J O D. (2001). Characterisation and properties of apoplastic herbicide metabolising carboxylesterases in wheat. Pesticide Biochemistry and Physiology 71 : 178 - 190.

1999

Maxwell K, Borland A M, Haslam R P, Helliker B R, Roberts A, Griffiths H. (1999). Modulation of Rubisco activity during the diurnal phases of the Crassulacean Acid Metabolism plant Kalanchoe daigremontiana. Plant Physiology 121 : 849 - 856.

Patent

Napier JA, Sayanova, O, Ruiz Lopez N, Haslam RP. (2013) The production of polyunsaturated fatty acids (PUFAs) in transgenic Camelina sp. plants WO2013153404 A1.

Senger T, Marty L, Stymne S, Lindberg Yilmaz J, Napier JA, Sayanova O, Haslam RP, Ruiz-Lopez, N.  (2011) Acyltransferases and uses therof in fatty acid production. WO/2011/161093.

Conference abstracts/posters (2008 to present)

Haslam R P (2015) Lipidomics in Agriculture. Mass Spectrometry in Food & Feed, 15th Sept, Ghent, Belgium.

Haslam R P, Napier JA (2015) The quantification of acyl-CoA in plants and microalgae.  5th European Lipidomics Meeting,2-4 September,  Swansea, UK.

Hamilton ML, Haslam R P, Warwick J, Allen M, Napier JA, Sayanova O. (2015) Engineering Phaeodactylum tricornutum for the enhanced Production of Omega-3 Long Chain Polyunsaturated Fatty Acids. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K.

Michaelson LV, Barrero-Sicilia C, Haslam R P. (2015) Deciphering the role of lipids in abiotic stress tolerance. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K

Usher S, Haslam R P, Betancor  M, SpragueM, CampbellPJ, Tocher DR, SayanovaO, NapierJA (2015) Using transgenic oil crops as sustainable animal feeds. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K.

Popko J,  Haslam R P, Hamilton ML, SayanovaO, NapierJA, Khozin-GoldbergI, HerrfurthC, FeussnerI (2015) Lipid Metabolism in P. tricornutum. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K

Gonzalez-Thuiller, I, Haslam R P, Tosi P, Salt L, Wilde P, Shewry, P R. (2015) The Role of Lipids in Determining Gas Bubble Retention and Stability in Wheat. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K

Gonzalez-Thuiller, I, Van-Erp, H, Haslam R P, Eastmond, PJ. (2015) Betaine lipids production in higher plants to improve plant phosphate use efficiency. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K

Ruiz-Lopez N, Haslam R P, Napier JA, Beaudoin F. (2015) Synthesis and Accumulation of different Profiles of Wax Esters in Camelina sativa Seeds. 5-8th July, 7th European Symposium on Plant Lipids, Rothamsted Research, Harpenden U.K

Michaelson LV, Barrero-Sicilia C, Haslam R P. (2015) Plant abiotic stress tolerance: unleashing lipids! 15-16th June, NIB Conference: healthy lives in a sustainable future, Rothamsted Research, Harpenden U.K.

Michaelson LV, Barrero-Sicilia C, Haslam R P. (2015) Deciphering the role of lipids in abiotic stress tolerance. GRC Plant Lipids and Metabolism, 1-6th Feb, Galveston, Texas, USA.

Haslam R P, Michaelson LV, Sayanova O, Napier, JA. (2014) Using lipidomics to unlock oilseed engineering. European Lipidomics Meetiing. 19-23rd Oct, Graz, Austria.

Haslam R P, Hamilton M L, Popko J, Herrforth C, Orf I, Khozin-Goldberg I, Feussner I, Napier J A, Sayanova O. (2014) Impact of Nitrogen depletion on the lipids of L. incisa. European Plant Microbial Lipids Meeting, 28-31st May, Hamburg, Germany.

Haslam R P, Michaelson LV, Ruiz-Lopez N, Sayanova O, Napier, JA. (2013) The transition from lipid analysis to lipidomics! Mini-Symposium on Long Chain n-3 Polyunsaturated Fatty Acids in the Human Diet - Health and Sustainability Issues. Rank Prize Meeting, 19-21st June, Grassmere, Lake District, U.K.

Haslam R P. (2012) Targeted Lipidomic Profiling: A Powerful Phenotyping Tool. Plenary Speaker, London Area Mass Spectrometry Society. 13th December, Gordon Museum, Hodgkins Building, King's College London, Guy's Campus, London.

Haslam R P, Michaelson L V, Napier JA. (2012) Plant lipidomics: talkin 'bout a revolution! 20th International Symposium on plant Lipids, 8-13th July, Seville, Spain.

Seamons L, Haslam R P, Bennett M, Napier J, Beaudoin F. (2012) Dissecting the role of very long chain fatty acids in Arabidopsis growth and development. 20th International Symposium on plant Lipids, 8-13th July, Seville, Spain.

Sayanova O,  Ruiz-Lopez N, Haslam R P, Usher S, Venegas Caleron M, Napier J A. (2012) Transgenic nutritional enhancement: the production of omega-3 long chain polyunsaturated fatty acids in plants. 20th International Symposium on plant Lipids, 8-13th July, Seville, Spain.

Joubes J, Pascal S, Bernard A, Sorel M, Haslam R P, Napier JA, Domergue F, Lessire R. (2012) The Arabidopsis cer26 mutant is specifically affected in VLCFA elongation process. 20th International Symposium on plant Lipids, 8-13th July, Seville, Spain.

Bernard A, Domergue F, Pascal S, Jetter R, Renne C, Faure J-D, Haslam R P, Napier J A, Lessire R, Joubes J. (2012) Reconstitution of plant alkane biosynthesis in yeast demonstrates that Arabidopsis CER1 and CER3 are core components of a VLC-alkane synthesis complex. 20th International Symposium on plant Lipids, 8-13th July, Seville, Spain.

Haslam R P. (2012) Targeted plant lipidomics and its application to designer seed oil. Conference series on new developments in LC/MS/MS. 27th June, ABSciex, The Oxford Belfry, Oxon, UK.

Joubes J, Pascal S, Bernard A, Sorel M, Haslam R P, Napier JA, Domergue F, Lessire R. (2011) The Arabidopsis cer26 mutant is specifically affected in VLCFA elongation process. 5th European Symposium on Plant lipids, 10 - 13th July, Gdansk, Poland.

Haslam R P, Ruiz-Lopez N, Sayanova O, Napier JA. (2011) Targeted lipid analysis in plants engineered for the production of VLC-PUFA. 5th European Symposium on Plant lipids, 10 - 13th July, Gdansk, Poland.

Olsson P, Zadravec D, Haslam R P, Napier J A, Jacobsson A. (2010) ELOVL2 Elongates Fatty Acids Crucial for Fertility and Normal Spermatogenesis in Male Mice. 8th EuroFed Lipid Congress, Munich, Germany, 21-24 November.

Ruiz-Lopez N, Haslam R P, Sayanova O, Napier J A. (2010) The production of Omega-3 Very Long-Chain Polyunsaturated Fatty Acids in transgenic plants: a sustainable source of omega-3 fish oils. Chemistry and Physics of Lipids 163 (Supplement 1) Page S17.

Theodoulou F L, Nyathi Y,  van RoermundC, De Marcos Lousa C,  LinkaN, ZhangX, Haslam R P, NapierJ A, Baldwin S A, WeberA, Baker A. (2010) Peroxisomal transporters associated with β-oxidation. Biochimica et Biophysica Acta – Bioenergetics 1797 Suppl. Page 46 EBEC Abstract Book. 

Sayanova O, Ruiz-Lopez N, Haslam R P, Li T, Napier J A. (2010) Plant Metabolic Engineering towards the Production of Optimised Levels of Omega-3 Very Long-chain Polyunsaturated Fatty Acids. 19th International Symposia on Plant Lipids, Cairns, Australia, 11 – 16th July.

Napier J A, Haslam R P, Faure J D, Beaudoin F. (2009) The synthesis of very long chain fatty acids: the role of the microsomal elongase. 7th Eurofed Lipid Congress, Graz, Austria, 18th - 21st Oct.

Haslam R P, Ruiz-Lopez N, Venegas Caleron M, Sayanova O, Napier J A. (2009) Heterologous production of stearidonic acid in transgenic oilseeds by expressing Primula n-3 specific fatty acid D6 desaturase. Gordon Plant Lipid Conference, Galveston, Texas, USA. 1st - 7th Feb.

Haslam R P, Venegas Caleron M, Sayanova O, Napier J A, Larson T R, Graham I A, Zank T, Bauer J. (2008) Journey to LC-PUFA production in Plants: Moving from Models to Crops. Lipgene Open Meeting, Dublin, Ireland, 4-5th December.

Napier J A, Sayanova O, Haslam R P, Li T, Ruiz Lopez N. (2008) Rational Metabolic Engineering of Transgenic Plants for the Biosynthesis of Omega-3 Polyunsaturates. 6th Eurofed Lipid Congress Athens, Greece. 7- 10th September.

Beaudoin F, Wu X, Li F, Haslam R P, Markham J, Zheng H, Napier J A, Kunst L. (2008) Functional Characterization of the Arabidopsis thaliana β -Ketoacyl-CoA Reductase Candidates of the Fatty Acid Elongase. 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Napier J A, Ruiz Lopez N, Li T, Venegas Caleron M, Haslam R P, Sayanova O. (2008) Optimising the accumulation of long chain polyunsaturates in transgenic plants. 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Michaelson L V, Zauner S, Markham J E, Haslam R P, Garton S, Albrecht S, Warnecke D, Sperling P, Heinz E, Napier J A. (2008). Investigating the role of the long chain base D4 desaturation in Arabidopsis. 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Furmanek T, Miklaszewska M, Bana, A, Haslam, R P, Napier J, Stymne S. (2008). The composition of the Acyl-CoA pool reflects fatty acid composition of the oil in developing seeds of Crambe abyssinica . 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Ruiz-Lopez N, Haslam R P, Sayanova O V, Napier J A. (2008) Heterologous production of stearidonic acid in transgenic oilseeds by expressing Primula n-3 specific fatty acid D6 desaturase. 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Sayanova O, Li T, Ruiz-Lopez N, Haslam R P, Napier J A. (2008) Enhancing ω - 3 LC-PUFAs biosynthesis in transgenic plants. 18th International Symposium on Plant Lipids, Bordeaux, France, 20-25th July.

Napier J A, Sayanova O, Haslam R P, Li T, Ruiz Lopez N. (2008). Rational Metabolic Engineering of Transgenic Plants for the Biosynthesis of Omega-3 Polyunsaturates. 6th Euro Fed Lipid Congress: Oils, Fats and Lipids in the 3rd Millennium: Challenges, Achievements and Perspectives, Athens , 7-10 September.